Yale School of Medicine

Research Studies at Yale

Research Studies at Yale

Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management

For Patients For Researchers

Condition: Marijuana Dependence

What is the purpose of this trial?

Cognitive-behavioral coping skills therapy (CBT) is a widely used and recognized treatment that has been empirically validated for a range of substance use disorders, often with emergent effects and continuing improvement even after treatment ends. Treatment retention and compliance are associated with enhanced treatment outcomes in CBT. Contingency management (CM) also has very strong support and is associated with rapid, robust effects on targeted outcomes. Despite their many strengths, neither CBT nor CM is universally effective. It is now essential to seek strategies to maximize and extend the effectiveness of these two approaches and to better understand how these treatments exert their effects.


Dates: December 2004 -
Study Status: Recruiting

Who can participate?

Ages Eligible: 18 Years - 65 Years
Gender Eligible: Both

Inclusion Criteria:

  • 18-65 year old marijuana dependent
  • willing to sign consent
  • no use of prescribed psychotropic drugs
  • willing to give three individuals as contacts
  • willing to accept randomization
  • read and write English (third grade level)

Exclusion Criteria:

  • unable to commit to 1 year follow up

Sponsor: National Institute on Drug Abuse (NIDA)
Phase: Phase 2

First Received: July 7, 2006 
Last Updated: Sep 14, 2009
Clinicaltrials.gov ID: NCT00350649
Study HIC # 0407026913

Condition: Marijuana Dependence

Interventions: Behavioral: Standard CBT;
Behavioral: CBT+CM/adherence;
Behavioral: CM/abstinence;
Behavioral: CM/abstinence+CBT

What is the purpose of this trial?

Cognitive-behavioral coping skills therapy (CBT) is a widely used and recognized treatment that has been empirically validated for a range of substance use disorders, often with emergent effects and continuing improvement even after treatment ends. Treatment retention and compliance are associated with enhanced treatment outcomes in CBT. Contingency management (CM) also has very strong support and is associated with rapid, robust effects on targeted outcomes. Despite their many strengths, neither CBT nor CM is universally effective. It is now essential to seek strategies to maximize and extend the effectiveness of these two approaches and to better understand how these treatments exert their effects.


show additional information...

Dates: December 2004 -
Study Status: Recruiting

Who can participate?

Ages Eligible: 18 Years - 65 Years
Gender Eligible: Both

Inclusion Criteria:

- 18-65 year old marijuana dependent

- willing to sign consent

- no use of prescribed psychotropic drugs

- willing to give three individuals as contacts

- willing to accept randomization

- read and write English (third grade level)

Exclusion Criteria:

- unable to commit to 1 year follow up


Additional Location

Connecticut

Sponsor: National Institute on Drug Abuse (NIDA)
Phase: Phase 2

First Received: July 7, 2006 
Last Updated: Sep 14, 2009
Clinicaltrials.gov ID: NCT00350649
Study HIC # 0407026913

Participate in this trial

For more information about this trial, contact:

JoAnna DePiono, BA
203-974-5731
joanna.depino@yale.edu

Rhonda Pruzinski, BA
203-974-5740
rhonda.pruzinski@yale.edu


Yale Researcher

Carroll, Kathleen M.
Principal Investigator  

HIC # 0805003779